Express 'since then' or 'after'; used to indicate that an action occurred once and has not been repeated or that a state has continued since a certain event or time.
Long explanation:
The ~たきり grammar point is used to express that an action occurred once and has not been repeated, or that a situation or state has continued since a certain event or time. It can be translated as 'since then', 'after' or 'one time only' in English.